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Ganjiwale, R. O.
- Development and Validation of Phyllanthin by HPTLC in Hepatoprotective Polyherbal Tablet Dosage Form
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1 P.G. Department of Quality Assurance, Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha-442001, Maharashtra, IN
1 P.G. Department of Quality Assurance, Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha-442001, Maharashtra, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 5 (2011), Pagination: 815-817Abstract
A simple, precise, accurate, rapid and reproductive HPTLC procedure was developed for development and validation of phyllanthin in tablet dosage form at a single wavelength. The mobile phase used was a combination of Toluene-Ethyl acetate [9:1 V/V]. The detection of the combined dosage form was carried out at 200nm. The Rf value of standard phyllanthin was 0.83 ± 0.04 and matches to the phyllanthin present in polyherbal tablet. The phyllanthin content of tablet was determined and it was found to be 0.178 % w/w ±0.0016.The results of the analysis were validated statistically and recovery studies confirmed the accuracy of the proposed method.Keywords
Polyherbal Tablets, Phyllanthin, HPTLC, Recovery.- The Preparation and Biological Evaluation of Some New 6-Iodo-2-Ethyl- 4(3H)-3 (5-Substituted Benzothiazole-2’-Yl) Quinazolinone Derivatives as an Anticonvulsant
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Authors
Affiliations
1 Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha-442001, IN
1 Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha-442001, IN